Structure Based Design of Potent Selective Inhibitors of Protein Kinase D1 (PKD1) | ACS Medicinal Chemistry Letters
NIK compounds* inhibit NFkB activation mediated by Smac-mimetic in MM... | Download Scientific Diagram
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
Transcreener ADP Assay Enables Evaluation of NIK Inhibitors in Lupus Drug Discovery - BellBrook Labs
TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation - Shiode - Hepatology - Wiley Online Library
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus | Nature Communications
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
NF-κB Signaling | NF-kappaB Pathway
The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth - ScienceDirect
The structure of Amgen NIK compounds. | Download Scientific Diagram
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
NIK as a Druggable Mediator of Tissue Injury: Trends in Molecular Medicine
NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis | Cell Death & Differentiation
Discovery of a Potent and Selective NF-κB-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo | Journal of Medicinal Chemistry
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases. - Abstract - Europe PMC
Cells | Free Full-Text | Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets
A Kinase Assay for Measuring the Activity of the NIK-IKK1 Complex Induced via the Noncanonical NF-κB Pathway | SpringerLink
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry
Small molecule approaches to treat autoimmune and inflammatory diseases (Part I): Kinase inhibitors - ScienceDirect
NIK as a Druggable Mediator of Tissue Injury: Trends in Molecular Medicine
IJMS | Free Full-Text | Small Molecule NF-κB Pathway Inhibitors in Clinic
Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00361A
NF-κB Inducing Kinase, a Central Signaling Component of the Non-Canonical Pathway of NF-κB, Contributes to Ovarian Cancer Progression | PLOS ONE
